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Table of Contents
LETTER TO THE EDITOR
Year : 2021  |  Volume : 4  |  Issue : 4  |  Page : 772-773

Authors' reply to Murmu et al.


1 Gujarat Cancer Society Medical College and Research Center, Ahmedabad, Gujarat, India
2 Department of Pathology, Gujarat Cancer Society Medical College and Research Center, Ahmedabad, Gujarat, India

Date of Submission08-Nov-2021
Date of Decision13-Nov-2021
Date of Acceptance13-Nov-2021
Date of Web Publication29-Dec-2021

Correspondence Address:
Puja Bhavesh Jarwani
Department of Pathology, Gujarat Cancer Society Medical College and Research Center, Opposite D.R.M. Office, Naroda Road, Near Chamunda Bridge, Ahmedabad, Gujarat
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/crst.crst_268_21

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How to cite this article:
Tahiliani HT, Purohit AP, Desai SC, Jarwani PB. Authors' reply to Murmu et al. Cancer Res Stat Treat 2021;4:772-3

How to cite this URL:
Tahiliani HT, Purohit AP, Desai SC, Jarwani PB. Authors' reply to Murmu et al. Cancer Res Stat Treat [serial online] 2021 [cited 2022 Jan 20];4:772-3. Available from: https://www.crstonline.com/text.asp?2021/4/4/772/334210



We thank Murmu et al. for reading our article titled, “Retrospective analysis of histopathological spectrum of premalignant and malignant colorectal lesions,” with interest and providing valuable comments.[1],[2] We completely agree with the comment that a cohort comprising only 150 patients is too small to draw any significant conclusions. However, similar studies have been conducted previously in different parts of India, and almost similar observations were reported by them.[3],[4]

We agree with Murmu et al. that the majority of the patients in our study had stage IIIB disease. Ours being a tertiary care center, patients with advanced disease are referred for treatment, which might have been the reason for the high proportion of patients with advanced stages of disease.

Murmu et al. are also correct in highlighting that additional patient information, such as antibiotic usage, whether the patient lived in an urban or rural region, level of daily physical activity of the patients, and their dietary habits, could have been recorded. However, this was beyond the scope of the study, which was focused mainly on the prevalence, distribution, and histopathological features of colorectal lesions.

We fully agree that large, well-designed cohort studies with valid control groups will be particularly critical in throwing more light on the etiology and increasing trend of colorectal cancers in India. We would again like to thank Murmu et al. for taking the time to review our article, raising concerns, and showing the way forward for further research regarding the increasing incidence of colorectal cancer in India.

Financial support and sponsorship

Nil.

Conflicts of interest

There are no conflicts of interest.



 
  References Top

1.
Tahiliani HT, Purohit AP, Desai SC, Jarwani PB. Retrospective analysis of histopathological spectrum of premalignant and malignant colorectal lesions. Cancer Res Stat Treat 2021;4:472-8.  Back to cited text no. 1
  [Full text]  
2.
Murmu N, Mitra D, Das G. Increasing incidence of colorectal cancer among Indians: Concerns and the way forward. Cancer Res Stat Treat 2021;4:771-2.  Back to cited text no. 2
  [Full text]  
3.
Sheikh B, Ambreen B, Summaiya F, Ruby R, FarzaanaM, Sheikh J. Spectrum of colorectal lesions on colonoscopic biopsies; a histopathological study in a tertiary care hospital. Int J Med Sci Clin Invent 2017;4:2750-8.  Back to cited text no. 3
    
4.
Padma S, Pramila R. Pattern of lower gastrointestinal diseases by colonoscopy and histopathological examination: A retrospective study. Int J Curr Res Rev 2018;10:20-5.  Back to cited text no. 4
    




 

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